The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2009
Filed:
Oct. 31, 2002
David H. Walker, Galveston, TX (US);
Xue-jie Yu, Galveston, TX (US);
David H. Walker, Galveston, TX (US);
Xue-Jie Yu, Galveston, TX (US);
Research Development Foundation, Carson City, NV (US);
Abstract
The 28-kDa outer membrane proteins (P28) ofare encoded by a multigene family consisting of 21 members located in a 23-kb DNA fragment in the genome of. Fifteen of these proteins are claimed herein as novel sequences. The amino acid sequence identity of the various P28 proteins was 20-83%. Six of 10 tested p28 genes were actively transcribed in cell culture grown. RT-PCR also indicated that each of the p28 genes was monocistronic. These results suggest that the p28 genes are active genes and encode polymorphic forms of the P28 proteins. The P28s were also divergent among different isolates of. The large repertoire of the p28 genes in a single ehrlichial organism and antigenic diversity of the P28 among the isolates ofsuggest that the P28s may be involved in immune avoidance.