The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2009
Filed:
Dec. 01, 2003
Jon Elliot Adler, San Diego, CA (US);
Sergey Zozulya, San Diego, CA (US);
Xiadong LI, San Diego, CA (US);
Shawn O'connell, Encinitas, CA (US);
Lena Staszewski, San Diego, CA (US);
Jon Elliot Adler, San Diego, CA (US);
Sergey Zozulya, San Diego, CA (US);
Xiadong Li, San Diego, CA (US);
Shawn O'Connell, Encinitas, CA (US);
Lena Staszewski, San Diego, CA (US);
Senomyx, Inc., San Diego, CA (US);
Abstract
Functional assays that use the T1R1 receptor to screen for taste modulatory compounds are provided. These assays include cell-based assays and high throughput compound assays to identify compounds that activate T1R1 or modulate T1R1 receptor activation by compound. Preferred functional assays detect the effect of a putative taste modulatory compound on cell voltage or intracellular calcium in a cell that expresses a T1R1 polypetide, preferably in association with a G protein, e.g. G{acute over (α)}15. Compounds identified using these assays have potential application as flavor enhancer and modulators in foods and beverage for human or animal consumption.