The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2009
Filed:
Mar. 11, 2002
Taro Kimura, Dazaifu, JP;
Masami Mizu, Sakai, JP;
Kazuo Sakurai, Himeji, JP;
Seiji Shinkai, Fukuoka, JP;
Kazuya Koumoto, Kurume, JP;
Taro Kimura, Dazaifu, JP;
Masami Mizu, Sakai, JP;
Kazuo Sakurai, Himeji, JP;
Seiji Shinkai, Fukuoka, JP;
Kazuya Koumoto, Kurume, JP;
Japan Science and Technology Agency, Tokyo, JP;
Mitsui Sugar Co., Ltd., Saitama, JP;
Fukuoka Prefectural Government, Fukuoka, JP;
Abstract
Disclosed are gene carriers utilizing β-1,3-glucan and methods of preparing the same. The β-1,3-glucan has at least one 1,6-glucopyranoside branch and is chemically modified through periodate oxidation and reductive amination so as to impart nucleic acid-binding functional groups (for example, cationic functional groups) to at least some of the 1,6-glucopyranoside branches thereof. Triple helix β-1,3-glucan is dissolved in a polar organic solvent to form single-stranded β-1,3-glucan. By replacing, in the presence of a nucleic acid, the polar organic solvent for the solution containing the chemically modified single-stranded β-1,3-glucan by water, a complex (gene carrier) is formed in which the nucleic acid is bound to double-stranded β-1,3-glucan.