The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2009
Filed:
Nov. 16, 2006
Louise C. Showe, Media, PA (US);
Michael Nebozhyn, Yeadon, PA (US);
Anil Vachani, Merion Station, PA (US);
Steven M. Albelda, Bala Cynwyd, PA (US);
Louise C. Showe, Media, PA (US);
Michael Nebozhyn, Yeadon, PA (US);
Anil Vachani, Merion Station, PA (US);
Steven M. Albelda, Bala Cynwyd, PA (US);
The Wistar Institute, Philadelphia, PA (US);
Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Abstract
The present invention is a method distinguishing between head and neck squamous cell carcinoma and lung squamous cell carcinoma. In particular, a 10-gene classifier has been identified which can be used to distinguish between primary squamous cell carcinoma of the lung and metastatic head and neck squamous cell carcinoma. These genes include CXCL13, COL6A2, SFTPB, KRT14, TSPYL5, TMP3, KLK10, MMP1, GAS1, and MYH2. A panel of one or more of these genes, or proteins encoded thereby, can be used for early diagnosis and selection of an appropriate therapeutic treatment.