The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2009

Filed:

Apr. 24, 2007
Applicants:

Kenneth L. Arrington, Philadelphia, PA (US);

Edward J. Brnardic, Lansdale, PA (US);

Vadim Y. Dudkin, Lansdale, PA (US);

Mark E. Fraley, North Wales, PA (US);

Shaei Y. Huang, Lansdale, PA (US);

Cheng Wang, King of Prussia, PA (US);

Inventors:

Kenneth L. Arrington, Philadelphia, PA (US);

Edward J. Brnardic, Lansdale, PA (US);

Vadim Y. Dudkin, Lansdale, PA (US);

Mark E. Fraley, North Wales, PA (US);

Shaei Y. Huang, Lansdale, PA (US);

Cheng Wang, King of Prussia, PA (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4738 (2006.01); C07D 471/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The instant invention provides for compounds which comprise substituted triazoloquinazolinones that inhibit CHK1 activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting CHK1 activity by administering the compound to a patient in need of treatment of cancer.


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