The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2009
Filed:
Feb. 24, 2004
Hideaki Shimizu, Tokyo, JP;
Atsuhiro Abe, Tokyo, JP;
Takashi Yaegashi, Tokyo, JP;
Seigo Sawada, Tokyo, JP;
Hideaki Shimizu, Tokyo, JP;
Atsuhiro Abe, Tokyo, JP;
Takashi Yaegashi, Tokyo, JP;
Seigo Sawada, Tokyo, JP;
Kabushiki Kaisha Yakult Honsha, Tokyo, JP;
Abstract
A method for preparing a novel crystalline polymorphic irinotecan hydrochloride which is excellent in the solubility in water and reduced in the content of impurities is provided. A method for preparing c-type crystals of irinotecan hydrochloride having diffraction peaks (2θ) at 9.15°, 10.00°, 11.80°, 12.20°, 13.00° and 13.40° in the powder X-ray diffractometry characterized by mixing irinotecan with one or more solvents selected from the group consisting of acetone, acetonitrile and tetrahydrofuran, adding hydrochloric acid, and collecting the formed crystals.