The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 20, 2009
Filed:
Feb. 22, 2000
Liang Xu, Arlington, VA (US);
Cheng-cheng Huang, Arlington, VA (US);
William Alexander, Rockville, MD (US);
Wenhua Tang, Arlington, VA (US);
Esther H. Chang, Chevy Chase, MD (US);
Liang Xu, Arlington, VA (US);
Cheng-Cheng Huang, Arlington, VA (US);
William Alexander, Rockville, MD (US);
WenHua Tang, Arlington, VA (US);
Esther H. Chang, Chevy Chase, MD (US);
SynerGene Therapeutics, Inc., Washington, DC (US);
Georgetown University, Washington, DC (US);
Abstract
Nucleic acid-immunoliposome compositions useful as therapeutic agents are disclosed. These compositions preferably comprise (i) cationic liposomes, (ii) a single chain antibody fragment which binds to a transferrin receptor, and (iii) a nucleic acid encoding a wild type p53. These compositions target cells which express transferrin receptors, e.g., cancer cells. These compositions can be used therapeutically to treat persons or animals who have cancer, e.g., head and neck cancer, breast cancer or prostate cancer.