The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 2009

Filed:

Oct. 12, 2005
Applicants:

Sean D. Monahan, Madison, WI (US);

Vladimir G. Budker, Middleton, WI (US);

Kirk Ekena, Middleton, WI (US);

Lisa Nader, Madison, WI (US);

Inventors:

Sean D. Monahan, Madison, WI (US);

Vladimir G. Budker, Middleton, WI (US);

Kirk Ekena, Middleton, WI (US);

Lisa Nader, Madison, WI (US);

Assignee:

Mirus Bio LLC, Madison, WI (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 48/00 (2006.01); C12N 15/88 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compositions and methods for delivery of proteins and peptides to mammalian cells in vitro are described. Specifically, polypeptide-surfactant complexes formed from noncovalent hydrophobation of polypeptides and reversible hydrophobic modification of polypeptides are described. The compositions can be used to delivery positively charged, negatively charged and charge neutral polypeptides to cells.


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