The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2008
Filed:
Oct. 19, 2005
Daniel Joseph Macool, Rutledge, PA (US);
Zhixiong Xue, Chadds Ford, PA (US);
Quinn Qun Zhu, West Chester, PA (US);
Daniel Joseph Macool, Rutledge, PA (US);
Zhixiong Xue, Chadds Ford, PA (US);
Quinn Qun Zhu, West Chester, PA (US);
E.I. du Pont de Nemours and Company, Wilmington, DE (US);
Abstract
The present invention relates to a fungal Cfatty acid elongase that is able to catalyze the conversion of palmitate (16:0) to stearic acid (18:0). Specifically, the nucleotide sequence of aCfatty acid elongase is provided (designated as 'ELO3'). Methods of increasing microbial oil production, increasing carbon flux into the polyunsaturated fatty acid biosynthetic pathway and increasing the content of polyunsaturated fatty acids by over-expression of the Cfatty acid elongase are described herein. Most desirably, the substrate specificity of the instant ELO3 will be particularly useful to enable accumulation of long-chain polyunsaturated fatty acids in oleaginous yeast, such as