The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2008
Filed:
Nov. 29, 2006
Vincent P. Mauro, San Diego, CA (US);
Gerald M. Edelman, La Jolla, CA (US);
Stephen A. Chappell, Del Mar, CA (US);
Frederick S. Jones, Cardiff, CA (US);
Geoffrey Owens, San Diego, CA (US);
Robyn Meech, San Diego, CA (US);
Vincent P. Mauro, San Diego, CA (US);
Gerald M. Edelman, La Jolla, CA (US);
Stephen A. Chappell, Del Mar, CA (US);
Frederick S. Jones, Cardiff, CA (US);
Geoffrey Owens, San Diego, CA (US);
Robyn Meech, San Diego, CA (US);
The Scripps Research Institute, La Jolla, CA (US);
Abstract
Provided are methods of identifying oligonucleotides having transcriptional or translational activity by integrating ilie oligonucleotide into a eukaryotic cell genome such that the oligonucleotide is operatively linked to an expressible polynucleotide, and detecting a change in expression of the expressible polynucleotide due to the operatively linked oligonucleotide. Also provided are vectors useful for identifying an oligonucleotide having transcriptional or translational regulatory activity according to a method of the invention. In addition, isolated synthetic transcriptional or translational regulatory elements identified according to a method of the invention are provided, as are kits, which contain a vector useful for identifying a transcriptional or translational regulatory element, or an isolated synthetic transcriptional or translational regulatory element or plurality of such elements. Also provided are isolated transcriptional regulatory elements.