The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2008

Filed:

Aug. 26, 2004
Applicants:

Bernd Buettelmann, Schopfheim, DE;

Simona Maria Ceccarelli, Basel, CH;

Georg Jaeschke, Basel, CH;

Sabine Kolczewski, Rheinfelden, DE;

Richard Hugh Philip Porter, Reinach, CH;

Eric Vieira, Frenkendorf, CH;

Inventors:

Bernd Buettelmann, Schopfheim, DE;

Simona Maria Ceccarelli, Basel, CH;

Georg Jaeschke, Basel, CH;

Sabine Kolczewski, Rheinfelden, DE;

Richard Hugh Philip Porter, Reinach, CH;

Eric Vieira, Frenkendorf, CH;

Assignee:

Hoffman-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to imidazole derivatives of formula I wherein R, R, R, R, X, Y and R are described hereinabove, or a pharmaceutically acceptable salt thereof. The invention also relates to a pharmaceutical composition comprising the imidazole derivatives of formula I, a process for preparing a compound of formula I, and a method of treating or preventing acute and/or chronic neurological disorder comprising administering to a patient in need of such treatment and/or prevention a therapeutically effective amount of said pharmaceutical composition. These disorders include Alzheimer's disease. These disorders also include mild cognitive impairment.


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