The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2008
Filed:
May. 31, 2002
Kathryn Rene Bracken, Morristown, NJ (US);
Joseph Ernest DE Los Angeles, Cranford, NJ (US);
Ying Huang, Olney, MD (US);
Michael Joseph Kadan, Adamstown, MD (US);
Gary Michael Ksander, Milford, NJ (US);
Dennis Bryan Zerby, Myersville, MD (US);
Kathryn Rene Bracken, Morristown, NJ (US);
Joseph Ernest de los Angeles, Cranford, NJ (US);
Ying Huang, Olney, MD (US);
Michael Joseph Kadan, Adamstown, MD (US);
Gary Michael Ksander, Milford, NJ (US);
Dennis Bryan Zerby, Myersville, MD (US);
Novartis AG, Basel, CH;
Abstract
Mutants of steroid receptor ligand binding domains and synthetic ligands which have specific binding affinities for these receptors are provided. The use of these LBD-ligand combinations for construction of selective 'molecular gene switches' is disclosed. Methods of regulating gene function using these switches are provided.