The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2008

Filed:

May. 05, 2006
Applicants:

Reiner L. Gentz, Gauting, DE;

Brent L. Kreider, Bedford, MA (US);

Jun Zhang, San Diego, CA (US);

Michael Antonaccio, New Hope, PA (US);

Donna Mendrick, Mount Airy, MD (US);

Pablo Jimenez, Chatham, NJ (US);

Vikram Patel, Germantown, MD (US);

Craig A. Rosen, Laytonsville, MD (US);

Mark D. Adams, Cleveland Heights, OH (US);

Haodong LI, Gaithersburg, MD (US);

Steven M. Ruben, Brookeville, MD (US);

Inventors:

Reiner L. Gentz, Gauting, DE;

Brent L. Kreider, Bedford, MA (US);

Jun Zhang, San Diego, CA (US);

Michael Antonaccio, New Hope, PA (US);

Donna Mendrick, Mount Airy, MD (US);

Pablo Jimenez, Chatham, NJ (US);

Vikram Patel, Germantown, MD (US);

Craig A. Rosen, Laytonsville, MD (US);

Mark D. Adams, Cleveland Heights, OH (US);

Haodong Li, Gaithersburg, MD (US);

Steven M. Ruben, Brookeville, MD (US);

Assignee:

Human Genome Sciences, Inc., Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/10 (2006.01); C12N 5/12 (2006.01); G01N 33/53 (2006.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
Abstract

There are disclosed therapeutic compositions and methods using isolated nucleic acid molecules encoding a human myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptide (previously termed MIP-3 and chemokine β8 (CKβ8 or ckb-8)); a human monocyte-colony inhibitory factor (M-CIF) polypeptide (previously termed MIP1-γ and chemokine β1(CKβ1 or ckb-1)), and a macrophage inhibitory protein-4 (MIP-4), as well as MPIF-1, M-CIF and/or MIP-4 polypeptides themselves, as are vectors, host cells and recombinant methods for producing the same.


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