The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2008
Filed:
Dec. 19, 2002
Hugh Y. Zhu, Scotch Plains, NJ (US);
F. George Njoroge, Warren, NJ (US);
Alan B. Cooper, West Caldwell, NJ (US);
Timothy J. Guzi, Chatham, NJ (US);
Dinanath F. Rane, Morganville, NJ (US);
Keith P. Minor, Sayerville, NJ (US);
Ronald J. Doll, Convent Station, NJ (US);
Viyyoor M. Girijavallabhan, Parsippany, NJ (US);
Bama Santhanam, Bridgewater, NJ (US);
Patrick A. Pinto, Morris Plains, NJ (US);
Bancha Vibulbhan, Kenilworth, NJ (US);
Kartik M. Keertikar, East Windsor, NJ (US);
Carmen S. Alvarez, Roselle Park, NJ (US);
John J. Baldwin, Gwynedd Valley, PA (US);
GE LI, Shanghai, CN;
Chia-yu Huang, Plainsboro, NJ (US);
Ray A. James, Plainsboro, NJ (US);
James J-s Wang, Westfield, NJ (US);
Jagdish A. Desai, Monroe Township, NJ (US);
Hugh Y. Zhu, Scotch Plains, NJ (US);
F. George Njoroge, Warren, NJ (US);
Alan B. Cooper, West Caldwell, NJ (US);
Timothy J. Guzi, Chatham, NJ (US);
Dinanath F. Rane, Morganville, NJ (US);
Keith P. Minor, Sayerville, NJ (US);
Ronald J. Doll, Convent Station, NJ (US);
Viyyoor M. Girijavallabhan, Parsippany, NJ (US);
Bama Santhanam, Bridgewater, NJ (US);
Patrick A. Pinto, Morris Plains, NJ (US);
Bancha Vibulbhan, Kenilworth, NJ (US);
Kartik M. Keertikar, East Windsor, NJ (US);
Carmen S. Alvarez, Roselle Park, NJ (US);
John J. Baldwin, Gwynedd Valley, PA (US);
Ge Li, Shanghai, CN;
Chia-Yu Huang, Plainsboro, NJ (US);
Ray A. James, Plainsboro, NJ (US);
James J-S Wang, Westfield, NJ (US);
Jagdish A. Desai, Monroe Township, NJ (US);
Schering Corporation, Kenilworth, NJ (US);
Pharmacopeia, Inc., Cranbury, NJ (US);
Abstract
Disclosed are novel tricyclic compounds represented by the formula (1.0): and a pharmaceutically acceptable salt or solvate thereof. The compounds are useful for inhibiting farnesyl protein transferase. Also disclosed are pharmaceutical compositions comprising compounds of formula 1.0. Also disclosed are methods of treating cancer using the compounds of formula 1.0.