The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 19, 2008
Filed:
Sep. 11, 2003
Richard M. Carlton, Port Washington, NY (US);
Carl R. Merril, Rockville, MD (US);
Sankar L. Adhya, Gaithersburg, MD (US);
Richard M. Carlton, Port Washington, NY (US);
Carl R. Merril, Rockville, MD (US);
Sankar L. Adhya, Gaithersburg, MD (US);
The United States of America as represented by the Department of Health and Human Services, Washington, DC (US);
Exponential Biotherapies, Inc., New York, NY (US);
Abstract
The present invention is directed to bacteriophage therapy, using methods which enable the bacteriophage to delay inactivation by any and all parts of the host defense system (HDS) against foreign objects. The HDS normally reduces the number of bacteriophage in an animal, which decreases the efficiency of the bacteriophage in killing the host bacteria present during an infection. Disclosed is a method of producing bacteriophage modified for anti-HDS purposes by physico-chemical alteration of the bacteriophage surface proteins, so that the altered bacteriophage remain active in the body for longer periods of time than the unmodified bacteriophage.