The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 22, 2008
Filed:
Sep. 13, 2005
Ying-fei Wei, Berkeley, CA (US);
Yi LI, Sunnyvale, CA (US);
Jian NI, Germantown, MD (US);
Craig A. Rosen, Laytonsville, MD (US);
Steven M. Ruben, Brookeville, MD (US);
Ying-Fei Wei, Berkeley, CA (US);
Yi Li, Sunnyvale, CA (US);
Jian Ni, Germantown, MD (US);
Craig A. Rosen, Laytonsville, MD (US);
Steven M. Ruben, Brookeville, MD (US);
Human Genome Sciences, Inc., Rockville, MD (US);
Abstract
The present invention relates to a novel CKα-5 protein which is a member of the alpha chemokine family. In particular, isolated nucleic acid molecules are provided encoding the human CKα-5 protein. CKα-5 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. Antibodies and fragments thereof that specifically bind to CKα-5 polypeptides are also disclosed, as are compositions and methods for making such antibodies. The invention further relates to screening methods for identifying agonists and antagonists of CKα-5 activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders.