The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 18, 2007

Filed:

Dec. 06, 2001
Applicants:

Petrus Jacobus Theodorus Dekker, Ae Den Haag, NL;

Luppo Edens, JL Rotterdam, NL;

Robertus Antonius Mijndert Van Der Hoeven, AJ Katwijk, NL;

Linda DE Lange, ML Gouda, NL;

Inventors:

Petrus Jacobus Theodorus Dekker, Ae Den Haag, NL;

Luppo Edens, JL Rotterdam, NL;

Robertus Antonius Mijndert Van Der Hoeven, AJ Katwijk, NL;

Linda De Lange, ML Gouda, NL;

Assignee:

DSM IP Assets B.V., Heerlen, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/48 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides An isolated polypeptide which has proline specific endoprotease activity, selected from the group consisting of:(a) a polypeptide which has an amino acid sequence which has at least 40% amino acid sequence identity with amino acids 1 to 526 of SEQ ID NO:2 or a fragment thereof;(b) a polypeptide which is encoded by a polynucleotide which hybridizes under low stringency conditions with (i) the nucleic acid sequence of SEQ ID NO:1 or a fragment thereof which is at least 80% or 90% identical over 60, preferably over 100 nucleotides, more preferably at least 90% identical over 200 nucleotides, or (ii) a nucleic acid sequence complementary to the nucleic acid sequence of SEQ ID NO:1.


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