The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 11, 2007

Filed:

Jul. 02, 2004
Applicants:

Stephen William Watson Michnick, Montreal, CA;

Marnie Macdonald, Pleasanton, CA (US);

John K. Westwick, San Ramon, CA (US);

Inventors:

Stephen William Watson Michnick, Montreal, CA;

Marnie MacDonald, Pleasanton, CA (US);

John K. Westwick, San Ramon, CA (US);

Assignee:

Odyssey Thera Inc., San Ramon, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12N 15/62 (2006.01);
U.S. Cl.
CPC ...
Abstract

The instant invention describes a method for detecting protein-protein interactions in living organisms and/or cells, said method comprising: (a) synthesizing probe protein fragments from a protein which enables fluorescent or luminescent detection by dissecting the gene coding for the fluorescent or luminescent protein into a least two fragments; (2) constructing fusion proteins consisting of the probe protein fragments linked to protein domains that are to be tested for interactions; (3) coexpressing the fusion proteins; and (d) detecting reconstitution of the fluorescence or luminescence signal.


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