The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2007
Filed:
Jul. 12, 2002
Gregory P. Pogue, Vacaville, CA (US);
John A. Lindbo, Vacaville, CA (US);
Michael J. Mcculloch, Vacaville, CA (US);
Jonathan E. Lawrence, Vacaville, CA (US);
Cynthia S. Gross, Vacaville, CA (US);
Stephen J. Garger, Vacaville, CA (US);
Gregory P. Pogue, Vacaville, CA (US);
John A. Lindbo, Vacaville, CA (US);
Michael J. McCulloch, Vacaville, CA (US);
Jonathan E. Lawrence, Vacaville, CA (US);
Cynthia S. Gross, Vacaville, CA (US);
Stephen J. Garger, Vacaville, CA (US);
Large Scale Biology Corporation, Vacaville, CA (US);
Abstract
The present invention relates to foreign peptide sequences fused to recombinant plant viral structural proteins and a method of their production. Fusion proteins are economically synthesized in plants at high levels by biologically contained tobamoviruses. The fusion proteins of the invention have are useful as antigens for inducing the production of antibodies having desired binding properties, e.g., protective antibodies, or for use as vaccine antigens for the induction of protective immunity against the parvovirus. Feline parvovirus epitopes were fused to the N-terminus of the TMV coat protein, expressed inplants, extracted, purified, characterized and administered to animals, resulting in protective immunity.