The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2007

Filed:

Jun. 14, 2004
Applicants:

Hidekazu Inoue, Osaka, JP;

Hidenobu Murafuji, Osaka, JP;

Yasuhiro Hayashi, Osaka, JP;

Inventors:

Hidekazu Inoue, Osaka, JP;

Hidenobu Murafuji, Osaka, JP;

Yasuhiro Hayashi, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/551 (2006.01); A61K 31/519 (2006.01); A61K 31/541 (2006.01); A61K 31/5355 (2006.01); C07D 243/08 (2006.01); C07D 487/04 (2006.01); C07D 417/12 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

Pyrazolopyrimidinone derivatives expressed by the following general formula (IA) or (IB): where the symbols are as disclosed in the specification, are provided as desired compounds. These compounds selectively inhibiting PDE7, thereby increasing the intracellular cAMP level and inhibiting the activation of T cells. Thus, these compounds are useful for prevention and treatment of various allergic diseases and inflammatory or immunological diseases.


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