The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 28, 2007

Filed:

Dec. 05, 2003
Applicants:

Mark E. Fraley, North Wales, PA (US);

Scott R. Hambaugh, Philadelphia, PA (US);

Robert S. Rubino, Williamsville, NY (US);

Randall W. Hungate, Newbury Park, CA (US);

Inventors:

Mark E. Fraley, North Wales, PA (US);

Scott R. Hambaugh, Philadelphia, PA (US);

Robert S. Rubino, Williamsville, NY (US);

Randall W. Hungate, Newbury Park, CA (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 413/04 (2006.01); A61K 31/519 (2006.01); A61K 31/535 (2006.01); A61P 35/00 (2006.01); A61P 3/08 (2006.01); A61P 19/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, macular edema, retinal ischemia, inflammatory diseases, and the like in mammals.


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