The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2007
Filed:
Oct. 22, 2001
Tim Keith, Bedford, MA (US);
Randall D. Little, Newtonville, MA (US);
Paul Van Eerdewegh, Weston, MA (US);
Josée Dupuis, Newton, MA (US);
Richard G. Del Mastro, Norfolk, MA (US);
Jason Simon, Westfield, NJ (US);
Kristina Allen, Hopkinton, MA (US);
Sunil Pandit, Gaithersburg, MD (US);
Tim Keith, Bedford, MA (US);
Randall D. Little, Newtonville, MA (US);
Paul Van Eerdewegh, Weston, MA (US);
Josée Dupuis, Newton, MA (US);
Richard G. Del Mastro, Norfolk, MA (US);
Jason Simon, Westfield, NJ (US);
Kristina Allen, Hopkinton, MA (US);
Sunil Pandit, Gaithersburg, MD (US);
Oscient Pharmaceuticals Corporation, Waltham, MA (US);
Abstract
This invention relates to genes identified from human chromosome 12q23-qter, which are associated with various diseases, including asthma. The invention also relates to the nucleotide sequences of these genes, isolated nucleic acids comprising these nucleotide sequences, and isolated polypeptides or peptides encoded thereby. The invention further relates to vectors and host cells comprising the disclosed nucleotide sequences, or fragments thereof, as well as antibodies that bind to the encoded polypeptides or peptides. Also related are ligands that modulate the activity of the disclosed genes or gene products. In addition, the invention relates to methods and compositions employing the disclosed nucleic acids, polypeptides or peptides, antibodies, and/or ligands for use in diagnostics and therapeutics for asthma and other diseases.