The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2007
Filed:
May. 15, 2002
Hiroo Matsumoto, Chiba, JP;
Takanori Shimizu, Chiba, JP;
Hiroo Matsumoto, Chiba, JP;
Takanori Shimizu, Chiba, JP;
Nissan Chemical Industries, Ltd., Tokyo, JP;
Daicel Chemical Industries, Ltd., Sakai, JP;
Abstract
A process for producing 2-cyclopropyl-4-(4-fluorophenyl)-quinoline-3-carbaldehyde important as intermediate for the synthesis of pharmaceuticals, efficiently from an unnecessary antipode, is provided. A process for producing 2-cyclopropyl-4-(4-fluorophenyl)-quinoline-3-carbaldehyde represented by the formula (III): which comprises treating a compound represented by the formula (I) or (II): (wherein A is —CHOH or —C(O)—, and R is a hydrogen atom, a Calkyl group which may be branched, a phenyl group, an alkali metal ion or an alkaline earth metal ion) with ozone, followed by reduction with an inorganic sulfur compound or by hydrogenation for reduction decomposition.