The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2007
Filed:
Dec. 28, 2004
Vasulinga Ravikumar, Carlsbad, CA (US);
Muthiah Manoharan, Weston, MA (US);
Daniel C. Capaldi, Carlsbad, CA (US);
Achim Krotz, San Diego, CA (US);
Douglas L. Cole, Half Moon Bay, CA (US);
Andrei P. Guzaev, Vista, CA (US);
Vasulinga Ravikumar, Carlsbad, CA (US);
Muthiah Manoharan, Weston, MA (US);
Daniel C. Capaldi, Carlsbad, CA (US);
Achim Krotz, San Diego, CA (US);
Douglas L. Cole, Half Moon Bay, CA (US);
Andrei P. Guzaev, Vista, CA (US);
Isis Pharmaceuticals, Inc., Carlsbad, CA (US);
Abstract
Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, phosphorodithioate, or other covalent linkages. The oligomers have substantially reduced exocyclic adducts deriving from acrylonitrile or related contaminants.