The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2007
Filed:
Apr. 30, 2004
Ponnampalam Gopalakrishnakone, Singapore, SG;
Maung-maung Thwin, Singapore, SG;
Wei-yi Ong, Singapore, SG;
Kazuki Sato, Higashi-ku, JP;
Ponnampalam Gopalakrishnakone, Singapore, SG;
Maung-Maung Thwin, Singapore, SG;
Wei-Yi Ong, Singapore, SG;
Kazuki Sato, Higashi-ku, JP;
National University of Singapore, Crescent, SG;
Abstract
Peptides that have potent PLA-inhibitory activity are disclosed. Homology searches of known PLA inhibitory molecules were used to identify and subsequently design potent peptide molecules that can induce neuroprotective as well as anti-inflammatory effect. These peptides were shown to protect against degeneration of joints in transgenic mouse model prone to arthritis. Protection from kainate-induced excitotoxic neuronal injury was also observed using these peptides. These peptides, their analogs and derivatives have potential as neuroprotective and/or anti-inflammatory agents in a clinical setting.