The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2007
Filed:
Jan. 31, 2004
Applicants:
Leone Dall'asta, Milan, IT;
Giovanni Cotticelli, Cernusco sul Naviglio, IT;
Inventors:
Leone Dall'asta, Milan, IT;
Giovanni Cotticelli, Cernusco sul Naviglio, IT;
Assignee:
Infosint SA, Cantoni Dei Grigioni, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/87 (2006.01);
U.S. Cl.
CPC ...
Abstract
There is described a process for the preparation of citalopram and of its pharmaceutically acceptable salts, which comprises treating a 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5 isobenzofurancarbaldoxime, O-substituted preferably with a diphenylmethyl or triphenylmethyl group, with formic-acetic anhydride. Furthermore, the total synthesis of citalopram, as free base or in form of its pharmaceutically acceptable salt, starting from 5-formylphthalide is described.