The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2007
Filed:
May. 04, 2001
Duncan Mcree, San Diego, CA (US);
Peter R. David, Palo Alto, CA (US);
Frank Von Delft, San Diego, CA (US);
John Rammelkamp, La Jolla, CA (US);
Enrique Abola, Encinitas, CA (US);
Duncan McRee, San Diego, CA (US);
Peter R. David, Palo Alto, CA (US);
Frank von Delft, San Diego, CA (US);
John Rammelkamp, La Jolla, CA (US);
Enrique Abola, Encinitas, CA (US);
Takeda San Diego, Inc., San Diego, CA (US);
Abstract
A method is provided for identifying a search model to use in molecular replacement for determining a structure of a target biomolecule, such as a protein, from X-ray diffraction data, the method comprising: employing computer executable logic to perform multiple molecular replacement searches on X-ray diffraction data of the target biomolecule where a group of different biomolecule structures are used as search models for the multiple molecular replacement searches; and employing computer executable logic to compare solutions from the multiple molecular replacement searches, the comparison producing data from which biomolecule structures can be identified as having superior structural identity with the target biomolecule as compared to the other biomolecule structures in the group.