The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2007

Filed:

Nov. 29, 2005
Applicants:

B. Narasimhulu Naidu, Durham, CT (US);

Jacques Banville, St-Hubert, CA;

Francis Beaulieu, Laprairie, CA;

Timothy P. Connolly, Portland, CT (US);

Mark R. Krystal, Westport, CT (US);

John D. Matiskella, Wallingford, CT (US);

Carl Ouellet, Boucherville, CA;

Serge Plamondon, Ste-Catherine, CA;

Roger Remillard, Napierville, CA;

Margaret E. Sorenson, Meriden, CT (US);

Yasutsugu Ueda, Clinton, CT (US);

Michael A. Walker, Durham, CT (US);

Inventors:

B. Narasimhulu Naidu, Durham, CT (US);

Jacques Banville, St-Hubert, CA;

Francis Beaulieu, Laprairie, CA;

Timothy P. Connolly, Portland, CT (US);

Mark R. Krystal, Westport, CT (US);

John D. Matiskella, Wallingford, CT (US);

Carl Ouellet, Boucherville, CA;

Serge Plamondon, Ste-Catherine, CA;

Roger Remillard, Napierville, CA;

Margaret E. Sorenson, Meriden, CT (US);

Yasutsugu Ueda, Clinton, CT (US);

Michael A. Walker, Durham, CT (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 33/42 (2006.01); C07D 267/14 (2006.01); C07D 279/02 (2006.01); C07D 205/08 (2006.01); C07F 90/542 (2006.01); A61K 31/533 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV


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