The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2006
Filed:
Mar. 08, 2004
Bernd Buettelmann, Schopfheim, DE;
Simona Maria Ceccarelli, Basel, CH;
Georg Jaeschke, Basel, CH;
Sabine Kolczewski, Rheinfelden, DE;
Richard Hugh Philip Porter, Reinach, CH;
Eric Vieira, Allschwil, CH;
Bernd Buettelmann, Schopfheim, DE;
Simona Maria Ceccarelli, Basel, CH;
Georg Jaeschke, Basel, CH;
Sabine Kolczewski, Rheinfelden, DE;
Richard Hugh Philip Porter, Reinach, CH;
Eric Vieira, Allschwil, CH;
Hoffmann-La Roche Inc., Nutley, NJ (US);
Abstract
The present invention provides 4-[1-Aryl-imidazol-4-ylethynyl]-2-alkyl-pyridine and 1-heteroaryl-imidazol-4-ylethynyl]-2-alkyl-pyridine derivatives and pharmaceutically acceptable salts thereof for the treatment or prevention of disorders mediated in full or in part by metabotropic glutamate receptor 5. These disorders include, e.g. acute, traumatic and chronic degenerative processes of the nervous system, such as Alzheimer's disease, senile dementia, Parkinson's disease, Huntington's chorea, amyotrophic lateral sclerosis and multiple sclerosis, psychiatric diseases, such as schizophrenia and anxiety, depression, pain and drug dependency.