The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 12, 2006

Filed:

Jul. 11, 2002
Applicants:

Stephen Delcardayre, Belmont, CA (US);

Matthew Tobin, San Jose, CA (US);

Willem P. C. Stemmer, Los Gatos, CA (US);

Jon E. Ness, Sunnyvale, CA (US);

Jeremy Minshull, Menlo Park, CA (US);

Phillip Patten, Menlo Park, CA (US);

Venkiteswatan Subramanian, San Diego, CA (US);

Linda A. Castle, Mountain View, CA (US);

Claus M. Krebber, Mountain View, CA (US);

Steve Bass, Hillsborough, CA (US);

Ying-xin Zhang, Redwood City, CA (US);

Tony Cox, Mountain View, CA (US);

Gjalt Huisman, San Carlos, CA (US);

Ling Yuan, El Marcero, CA (US);

Joseph A. Affholter, Saratoga, CA (US);

Inventors:

Stephen delCardayre, Belmont, CA (US);

Matthew Tobin, San Jose, CA (US);

Willem P. C. Stemmer, Los Gatos, CA (US);

Jon E. Ness, Sunnyvale, CA (US);

Jeremy Minshull, Menlo Park, CA (US);

Phillip Patten, Menlo Park, CA (US);

Venkiteswatan Subramanian, San Diego, CA (US);

Linda A. Castle, Mountain View, CA (US);

Claus M. Krebber, Mountain View, CA (US);

Steve Bass, Hillsborough, CA (US);

Ying-Xin Zhang, Redwood City, CA (US);

Tony Cox, Mountain View, CA (US);

Gjalt Huisman, San Carlos, CA (US);

Ling Yuan, El Marcero, CA (US);

Joseph A. Affholter, Saratoga, CA (US);

Assignee:

Maxygen, Inc., Redwood City, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/16 (2006.01); C12N 1/18 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.


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