The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2006
Filed:
Feb. 06, 2003
Applicants:
Igal Madar, Baltimore, MD (US);
Hayden T. Ravert, Bel Air, MD (US);
Robert Francis Dannals, Sparks, MD (US);
Ursula A. Scheffel, Baltimore, MD (US);
James J. Frost, Baltimore, MD (US);
Inventors:
Igal Madar, Baltimore, MD (US);
Hayden T. Ravert, Bel Air, MD (US);
Robert Francis Dannals, Sparks, MD (US);
Ursula A. Scheffel, Baltimore, MD (US);
James J. Frost, Baltimore, MD (US);
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides a series of lipophilic phosphonium cations (PhCs) labeled withF for non-invasive assessment of ΔΨm, lipophilic ammonium cation analogs of the PhCs, and methods of using same for imaging and detection of mitochondrial-related pathologies in patients using PET or SPECT.