The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 19, 2006
Filed:
Feb. 22, 2002
Lori Clarke, Olney, MD (US);
Mario Gorziglia, Doleystown, PA (US);
Paul L. Hallenbeck, Gaithersburg, MD (US);
John Leonard Jakubczak, Germantown, MD (US);
Michael Kaleko, Rockville, MD (US);
Sandrina Phipps, Reston, VA (US);
Lori Clarke, Olney, MD (US);
Mario Gorziglia, Doleystown, PA (US);
Paul L. Hallenbeck, Gaithersburg, MD (US);
John Leonard Jakubczak, Germantown, MD (US);
Michael Kaleko, Rockville, MD (US);
Sandrina Phipps, Reston, VA (US);
Cell Genesys, Inc., South San Francisco, CA (US);
Abstract
The present invention provides novel viral vectors and methods useful for the minimization of leaky gene expression, and, in particular, of nonspecific transcriptional read-through of genes. Such constructs may be obtained by the insertion of an insulating sequence into a vector construct, such as for example a termination signal sequence upstream of the transcription initiation site of the respective transcription unit.