The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2006
Filed:
Nov. 19, 2002
Kalevi Visuri, Kirkkonummi, FI;
Sinikka Uotila, Espoo, FI;
Scott P. Fulton, Middleton, WI (US);
Daniel E. Couto, Chelsea, MA (US);
Kalevi Visuri, Kirkkonummi, FI;
Sinikka Uotila, Espoo, FI;
Scott P. Fulton, Middleton, WI (US);
Daniel E. Couto, Chelsea, MA (US);
GTC Biotherapeutics, Inc., Framingham, MA (US);
Abstract
The present invention relates to the purification and production of human albumin from various sources through crystallization and repeated crystallization. Basic features of the invented process include providing specific reaction conditions and precipitating reagents to maximize albumin crystallization. Solubility diagrams are utilized as the basis for process control of the invented method. The current invention specifically controls phosphate concentration, pH and temperature to precisely guide crystallization kinetics and crystal yield.