The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2006
Filed:
Jul. 26, 2002
Matthew Ashby, Mill Valley, CA (US);
Stewart Scherer, Moraga, CA (US);
John W. Phillips, Kirkland, WA (US);
Michael Ziman, Seattle, WA (US);
Nicholas Marini, San Francisco, CA (US);
Matthew Ashby, Mill Valley, CA (US);
Stewart Scherer, Moraga, CA (US);
John W. Phillips, Kirkland, WA (US);
Michael Ziman, Seattle, WA (US);
Nicholas Marini, San Francisco, CA (US);
Rosetta Inpharmatics LLC, Seattle, WA (US);
Abstract
The present invention relates to methods of identifying genes whose expression is indicative of activation of a particular biochemical or metabolic pathway or a common set of biological reactions or functions in a cell ('regulon indicator genes') The present invention provides an example of such an indicator gene. The present invention also relates to methods of partially characterizing a gene of unknown function by determining which biological pathways, reactions or functions its expression is associated with, thereby placing the gene within a functional genetic group or 'regulon'. These partially characterized genes may be used to identify desirable therapeutic targets of biological pathways of interest (“regulon target genes”) The present invention provides examples of such target genes. Methods for identifying effectors (activators and inhibitors) of regulon target genes are provided. The present invention also provides examples of regulon target gene inhibitors.