The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2006

Filed:

Jul. 18, 2002
Applicants:

Junming Le, Jackson Heights, NY (US);

Jan Vilcek, New York, NY (US);

Peter Daddona, Menlo Park, CA (US);

John Ghrayeb, Thorndale, PA (US);

David Knight, Berwyn, PA (US);

Scott Siegel, Westborough, MA (US);

Inventors:

Junming Le, Jackson Heights, NY (US);

Jan Vilcek, New York, NY (US);

Peter Daddona, Menlo Park, CA (US);

John Ghrayeb, Thorndale, PA (US);

David Knight, Berwyn, PA (US);

Scott Siegel, Westborough, MA (US);

Assignees:

New York University, New York, NY (US);

Centocor, Inc., Malvern, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-α (TNFα) and are useful in vivo diagnosis and therapy of a number of TNFα-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.


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