The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2006
Filed:
Nov. 13, 2002
Tianbao LU, Kennett Square, PA (US);
Louis V Lafrance, Iii, West Chester, PA (US);
Daniel J Parks, Exton, PA (US);
Karen L Milkiewicz, Exton, PA (US);
Raul R Calvo, Royersford, PA (US);
Maxwell D Cummings, Wayne, PA (US);
Alexander J Kim, Philadelphia, PA (US);
Bruce L Grasberger, Trappe, PA (US);
Theodore E Carver, Jr., Downingtown, PA (US);
Tianbao Lu, Kennett Square, PA (US);
Louis V Lafrance, III, West Chester, PA (US);
Daniel J Parks, Exton, PA (US);
Karen L Milkiewicz, Exton, PA (US);
Raul R Calvo, Royersford, PA (US);
Maxwell D Cummings, Wayne, PA (US);
Alexander J Kim, Philadelphia, PA (US);
Bruce L Grasberger, Trappe, PA (US);
Theodore E Carver, Jr., Downingtown, PA (US);
Other;
Abstract
The present invention is directed to novel 1,4-benzodiazepines, pharmaceutical compositions thereof, and the use thereof as inhibitors of HDM2-p53 interactions. Compounds have Formula I: or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein: