The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2006
Filed:
Nov. 14, 2002
Takashi Horiuchi, Funabashi, JP;
Masamichi Shimizu, Funabashi, JP;
Shoichi Kondo, Funabashi, JP;
Tadashi Soejima, Hiratsuka, JP;
Kazuhiro Umeo, Hiratsuka, JP;
Takashi Horiuchi, Funabashi, JP;
Masamichi Shimizu, Funabashi, JP;
Shoichi Kondo, Funabashi, JP;
Tadashi Soejima, Hiratsuka, JP;
Kazuhiro Umeo, Hiratsuka, JP;
Nissan Chemical Industries, Ltd., Tokyo, JP;
Sankyo Chemical Industries, Ltd., Tokyo, JP;
Abstract
A novel process for producing an optically active (E)-7-[2-cyclopropyl-4-(4-fluorophenyl quinolin-3-yl]-5-hydroxy-3-oxohept-6-enoic acid ester of formula (III) which is important as an intermediate for synthesizing medicines, comprises reacting 1,3-bis(trimethylsilyloxy)-1-alkoxybuta-1,3-diene of formula (I) with (E)-3-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-prop-2-en-1-al of formula (II) in the presence of an optically active binaphthol-titanium complex obtained from 1,1'-bi-2-naphthol with titanium tetraisopropoxide, a metal salt and an amine, and then subjecting the reaction product to desilylation
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile