The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2006
Filed:
Apr. 27, 2001
Joseph Roberts, Columbia, SC (US);
Thomas W Macallister, Columbia, SC (US);
Natarajan Sethuraman, Columbia, SC (US);
Abbie G. Freeman, Columbia, SC (US);
Joseph Roberts, Columbia, SC (US);
Thomas W MacAllister, Columbia, SC (US);
Natarajan Sethuraman, Columbia, SC (US);
Abbie G. Freeman, Columbia, SC (US);
ME Medical Enzymes AG, Berlin, DE;
Other;
Abstract
DNA encoding a therapeutically suitable glutaminase has been molecularly cloned. This allows one to obtain a polypeptide which is a therapeutically suitable glutaminase free of contaminating endotoxin. It has been found that this polypeptide is a potent anti-viral agent and when coupled to an anti-tumor monoclonal antibody is a potent anticancer agent. The glutaminase of the present invention is particularly useful for treating lung, breast and colon cancer cells and in the treatment of HIV-infected cells.