The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2006
Filed:
Mar. 22, 2002
Kenichi Tokunaga, Chiba, JP;
Masami Kozawa, Chiba, JP;
Kenji Suzuki, Chiba, JP;
Nissan Chemical Industries, Ltd., Tokyo, JP;
Abstract
A method for preparing a 7-quinolynyl-3,5-dihydroxyhept-6-enoate useful as an intermediate for pharmaceuticals, in high yield and in high purity, is presented. It is a method for preparing a 7-quinolinyl-3,5-dihydroxyhept-6-enoate represented by the formula (IV):(wherein R represents an alkyl group or an aryl group), characterized in that a compound represented by the formula (I):(wherein R is as defined above), or a compound represented by the formula (II):(wherein R is as defined above), is reduced by sodium borohydride in the presence of a boron compound represented by the formula (III):R'OBR″  (III)(wherein R′ and R″ represent independently an alkyl group), and then the resultant reaction mixture is treated with an aqueous solution of hydrogen peroxide.