The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2006
Filed:
Jun. 05, 1995
Ronald M. Evans, La Jolla, CA (US);
Steven A. Kliewer, San Diego, CA (US);
Kazuhiko Umesono, La Jolla, CA (US);
Ronald M. Evans, La Jolla, CA (US);
Steven A. Kliewer, San Diego, CA (US);
Kazuhiko Umesono, La Jolla, CA (US);
The Salk Institute for Biological Studies, La Jolla, CA (US);
Abstract
In accordance with the present invention, it has been discovered that various members of the steroid/thyroid superfamily of receptors can interact to form multimeric species comprising a complex of more than one receptor. Accordingly, the interaction of a first receptor species with a second receptor species modulates the ability of the first receptor species to trans-activate transcription of genes maintained under hormone expression control in the presence of the cognate ligand for said first receptor.