The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2006

Filed:

May. 23, 2003
Applicants:

David B. Rozema, Madison, WI (US);

Darren Wakefield, Madison, WI (US);

Jon A. Wolff, Madison, WI (US);

Kirk Ekena, Madison, WI (US);

James E. Hagstrom, Middleton, WI (US);

Inventors:

David B. Rozema, Madison, WI (US);

Darren Wakefield, Madison, WI (US);

Jon A. Wolff, Madison, WI (US);

Kirk Ekena, Madison, WI (US);

James E. Hagstrom, Middleton, WI (US);

Assignee:

Mirus Bio Corporation, Madison, WI (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

An process for the reversible modification of membrane interaction of a compound is described. Modification of membrane interaction can be used to facilitate delivery of molecules to cells in vitro and in vivo. The described modifiers, which are used to reversibly inactivate the membrane active compounds, can also be utilized as cross-linkers or to reverse the charge of a molecule.


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