The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2006
Filed:
Aug. 21, 2000
José L. Boyer, Chapel Hill, NC (US);
Gillian M. Olins, Cary, NC (US);
Benjamin R. Yerxa, Raleigh, NC (US);
James G. Douglass, Iii, Apex, NC (US);
José L. Boyer, Chapel Hill, NC (US);
Gillian M. Olins, Cary, NC (US);
Benjamin R. Yerxa, Raleigh, NC (US);
James G. Douglass, III, Apex, NC (US);
Inspire Pharmaceuticals, Inc., Durham, NC (US);
University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Abstract
The present invention provides novel compounds of dinucleotide polyphosphates and the method of preventing or treating diseases or conditions associated with platelet aggregation. The method comprises administering systemically to a patient a pharmaceutical comprising a purinergic P2receptor antagonist, in an amount effective to elevate its extracellular concentration to bind to P2receptors and inhibit P2receptor-mediated platelet aggregation. Methods of systemic administration include injection by intravenous, intramuscular, intrasternal and intravitreal routes, infusion, transdermal administration, oral administration, rectal administration and intra-operative instillation.