The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2006
Filed:
Aug. 24, 2000
Keizo Inoue, Koto-ku, Tokyo 135-0044, JP;
Hiroyuki Arai, Bunkyo-ku, Tokyo 112-0002, JP;
Makoto Arita, Kanagawa, JP;
Kou-ichi Jishage, Shizuoka, JP;
Hiroshi Suzuki, Shizuoka, JP;
Keizo Inoue, Koto-ku, Tokyo 135-0044, JP;
Hiroyuki Arai, Bunkyo-ku, Tokyo 112-0002, JP;
Makoto Arita, Kanagawa, JP;
Kou-ichi Jishage, Shizuoka, JP;
Hiroshi Suzuki, Shizuoka, JP;
Other;
Abstract
The present invention provides a knockout animal artificially modified to inhibit α-TTP gene expression. This animal is useful as a tool for understanding mechanisms for the development of familial isolated vitamin E deficiency and other diseases induced by oxidative stress (e.g., arteriosclerosis, diabetes). It is also useful as a tool for developing a therapeutic agent for these diseases.