The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2005
Filed:
Sep. 06, 2002
Sek Wen Hui, Williamsville, NY (US);
Arindam Sen, Williamsville, NY (US);
Sek Wen Hui, Williamsville, NY (US);
Arindam Sen, Williamsville, NY (US);
Health Research, Inc., Buffalo, NY (US);
Abstract
The present invention provides a liposomal composition for targeted delivery of drugs. The composition comprises large unilamellar vesicles (LUV) encapsulating poloxamers and one or more delivery agents. The composition and concentration of the poloxamer inside the LUVs is such that upon heating to temperatures above the critical micellar temperature of the poloxamer, the LUVs becomes leaky causing release of the encapsulated drug. The present invention also provides a method for delivery of agents to targeted sites and a method for preparing the LUVs suitable for use according to the method described herein.