The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2005
Filed:
Jul. 13, 2001
Joseph M. Jacobson, Newton, MA (US);
John J. Schwartz, Newtonville, MA (US);
Kimberly Hamad, Cambridge, MA (US);
Shuguang Zhang, Lexington, MA (US);
Joseph M. Jacobson, Newton, MA (US);
John J. Schwartz, Newtonville, MA (US);
Kimberly Hamad, Cambridge, MA (US);
Shuguang Zhang, Lexington, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
Methods and compositions for rendering nucleic acids directly responsive to an external signal utilizing modulators that themselves respond to the external signal and are associated with the nucleic acid. In response to the external signal, the modulator alters physical properties of the specific nucleic acid molecule(s) with which it is associated, thereby altering the structural and functional properties thereof. The modulator may, for example, transfer applied energy to a nucleic acid, or to a portion of the nucleic acid, thereby changing the nucleic acid structure.