The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2005
Filed:
Oct. 24, 2001
Thomas J. Wickham, Germantown, MD (US);
Imre Kovesdi, Rockville, MD (US);
Douglas E. Brough, Gaithersburg, MD (US);
Thomas J. Wickham, Germantown, MD (US);
Imre Kovesdi, Rockville, MD (US);
Douglas E. Brough, Gaithersburg, MD (US);
GenVec, Inc., Gaithersburg, MD (US);
Abstract
The present invention provides a recombinant adenovirus comprising coat proteins that lack native binding. In particular, the present invention provides a recombinant adenovirus comprising a penton base protein and a fiber protein, wherein the penton base protein and the fiber protein lack native binding. The present invention further provides a recombinant adenovirus comprising (a) a penton base protein that lacks native binding and (b) a nonnative amino acid sequence that binds a cell-surface binding site.