The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2005

Filed:

Sep. 08, 2000
Applicants:

Jonathan P. Duvick, Des Moines, IA (US);

Jacob T. Gilliam, Norwalk, IA (US);

Joyce R. Maddox, Omaha, NE (US);

Aragula Gururaj Rao, Urbandale, IA (US);

Oswald R. Crasta, Branford, CT (US);

Otto Folkerts, Guilford, CT (US);

Inventors:

Jonathan P. Duvick, Des Moines, IA (US);

Jacob T. Gilliam, Norwalk, IA (US);

Joyce R. Maddox, Omaha, NE (US);

Aragula Gururaj Rao, Urbandale, IA (US);

Oswald R. Crasta, Branford, CT (US);

Otto Folkerts, Guilford, CT (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N015/09 ; C12N015/31 ; C12N015/82 ; A10H001/00 ; A10H005/10 ;
U.S. Cl.
CPC ...
Abstract

The present invention provides polynucleotides and related polypeptides of the enzyme APAO isolated fromand. The polynucleotides may be mutated to remove glycosylation sites and cysteine residues. Additionally, the present invention provides recombinant expression cassettes, host cells, transgenic plants, and transgenic seed. The present invention also provides for polynucleotides containing both APAO and a fumonisin esterase. In addition, the present invention provides methods for producing the APAO enzyme in both prokaryotic and eukaryotic systems, methods for detecting fumonisins, and methods for identifying transformed plant cells. Methods for degrading fungal toxins in plants, grain, grain processing, silage, food crops and in animal feed are also disclosed.


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