The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2005
Filed:
Dec. 19, 2001
William A. Mcmillan, Cupertino, CA (US);
Lee A. Christel, Palo Alto, CA (US);
David A. Borkholder, San Jose, CA (US);
Steven J. Young, Los Gatos, CA (US);
William A. McMillan, Cupertino, CA (US);
Lee A. Christel, Palo Alto, CA (US);
David A. Borkholder, San Jose, CA (US);
Steven J. Young, Los Gatos, CA (US);
Cepheid, Sunnyvale, CA (US);
Abstract
An apparatus for determining a threshold value (e.g., a threshold cycle number or a time value) in a nucleic acid amplification reaction comprises a detection mechanism for measuring, at a plurality of different times during the amplification reaction, at least one signal whose intensity is related to the quantity of a nucleic acid sequence being amplified in the reaction. A controller in communication with the detection mechanism is programmed to store signal values defining a growth curve for the nucleic acid sequence, determine a derivative of the growth curve, and calculate a cycle number or time value associated with a characteristic of the derivative.