The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 12, 2005

Filed:

Jun. 21, 2002
Applicants:

Reiner L. Gentz, Silver Spring, MD (US);

Tsu-an Hsu, Harleysville, PA (US);

Craig A. Rosen, Laytonsville, MD (US);

Jian NI, Rockville, MD (US);

Inventors:

Reiner L. Gentz, Silver Spring, MD (US);

Tsu-An Hsu, Harleysville, PA (US);

Craig A. Rosen, Laytonsville, MD (US);

Jian Ni, Rockville, MD (US);

Assignee:

Human Genome Sciences, Inc., Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N033/48 ; G01N033/53 ; G01N033/573 ; G01N033/86 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to a novel TFPI-3 protein which is a member of the tissue factor protease inhibitor family. In particular, isolated nucleic acid molecules are provided encoding human TFPI-3 proteins. TFPI-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TFPI-3 activity. Also provided are diagnostic methods for detecting hemostasis system-related disorders and therapeutic methods for treating hemostatis system-related disorders.


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