The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2005
Filed:
Jan. 24, 2003
Applicants:
Michael B. Kastan, Cordova, TN (US);
Christopher Bakkenist, Cordova, TN (US);
Inventors:
Michael B. Kastan, Cordova, TN (US);
Christopher Bakkenist, Cordova, TN (US);
Assignee:
St. Jude Children's Research Hospital, Memphis, TN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N009/12 ; G01N033/53 ; G01N033/567 ; G01N003/537 ; G01N003/543 ;
U.S. Cl.
CPC ...
Abstract
The present invention provides methods for detecting activation of ATM kinase, DNA damage, and DNA damaging agents. Further provided are antibodies which specifically recognize the phosphorylation state of Ataxia Telangiectasia-Mutated (ATM) kinase. Methods of identifying agents which modulate the activation and activity of ATM kinase are also provided.